Why can someone afford the cakes every day and see a slim silhouette in the mirror? And someone sits on water and celery, spends days and nights in the gym, but continues to gain weight? Or it happens like this: a girlfriend lost weight on a new diet, however, follow the whole prescription, become more rounded?
Sometimes the reason is that it is not exactly that one or another method of weight loss is individually. To understand in which direction to move, sometimes you should not try to try all the ways in a row, and find your own, individual.
That is why recently the possibility of feeding nutrition and physical loads on DNA appeared. In the US, such tests are used everywhere, but in Russia we only come to the fact that everyone needs an individual approach. Yes, it is impossible to change the structure of the studied genes, but we are able to positively affect their work in those moments when we drink, eat, we take vitamins or medical drugs, make exercise, choose the mode of operation and recreation.
- How long have it been to use DNA tests to determine the factors of health? Why did you decide that this is a productive method?
- The first DNA tests that can be ordered, without a doctor, appeared in the early 2000s. Already then many became clear: such tests, if they are correctly interpreted and then adjust your lifestyle, are a powerful tool, "says Marina Vieva , BEYOUNGBRANDS founder, health, nutrition specialist, epigenetics, interval and DNA tests. - After all, our genes do not change throughout the life, but depending on what and how we do, they can affect our health - in a good or bad key. For example, "good" genes can continue to work perfectly or even better, and the "bad" gene can either grow into a disease or remain latent all life.
Marina Vieva, Health Specialist, Nutriciology, Epigenetics, Interval Power and DNA Tests
Photo: Personal archive
How strongly the genes affect what diseases can we manifest yourself?
Monogenic diseases have the largest percentage of the transmission probability by inheritance, and they are numbered by different estimates of up to 10 thousand, while about 5 thousand were studied. However, such diseases are quite rare and their cases in a population from 1:10,000 to 1: 1,000,000. But the likelihood of the development of multifactorial diseases (those most often found and the main of which we are known) more depends on the environment and Human lifestyle style than from inherited genes. Multifactorous diseases include diseases from which dying most often - heart disease, high pressure, diabetes, cancer, obesity, arthritis, Alzheimer's disease. In order to identify the data of the predisposition, it is worth passing the DNA test as early as possible to change the lifestyle and not give the disease to develop.
That is, it turns out that cancer is not inherited and only our lifestyle affects its development?
According to research, most of the oncological diseases do not relate to hereditary cancer, and often the result of the transition of precancerous diseases into it. Less than 10% of oncological diseases can be inherited, and then only the predisposition to cancer is genetically transmitted, and not the disease itself. Plus, the risk of its occurrence is different, depends on the specific type of cancer. For example, breast cancer is very high likelihood.
Since we do not change the genes during life, does this mean that the DNA test is surrendered once in a lifetime?
If we take the same genes and polymorphisms, then yes, the test is surrendered once. But the fact is that there are quite a lot of them and not all of them are still deciphered. For example, in the dietary test, 62 genes are considered, and in the test "active longevity" - 46, some of them intersect. In the United States, there are tests where as much as 93 gene can be checked, but for now, of course, the pleasure is not cheap. You can check DNA portion: first to pass by 10-20 most critical genes, and then there is already additional panels - watch any other predispositions. But yes, the same genes and polymorphisms should not be rechecked for life, as they remain unchanged. And here's how they will manifest in life, another question.
Tell us how does the procedure generally happen? How are predispositions?
To begin with saliva, from the inside of the cheek, the biomaterial is going. And then, when it enters the laboratory, the sequencing process occurs on special equipment. Thus, for each panel, genes are found and checked for polymorphisms in them. There we can see, for example, a polymorphism of a gene with poor absorbability of lactose or a tendency to overeat, respectively, a report with individual predispositions.
Does this mean that the test results are more recommendations than clear instructions for action?
Yes exactly. The results of DNA tests are not diagnoses, they are generally banned, based on the results. But it happens that recommendations may be more convincing. This happens, in particular, with a combination of certain polymorphisms. For example, with insufficient lipid metabolism, a tendency to overeating and diabetes, here, rather, there will be instructions for the action, rather than just recommendations. But, of course, they are prescribed in an exceptional manner by the doctor.
But in general, the genetic test should be done to all or only those who already have complaints?
I think this is: if a person is absolutely healthy, then the test is still worth passing, but at 28-30 years old. It is believed that precisely at this age begins the process of aging, this is a kind of turning point. But it is important to take into account that now many live in megalopolis, plus in the modern rhythm of life have many lame nutrition, so maybe this moment comes even earlier than 28 years. But in general - yes, at this age, we have the redistribution of everything in our system and if before this time our own resources could organize the maximum number of external factors and unhealthy food, then after 28 it will all decrease and, accordingly, negative factors will manifest And affect health to an even greater degree. Well, of course, it is worth noting that if there are any inclined, precedents, family history, then than before you pass the test, the better.
There are many of their varieties on the DNA DNA market. Tell me, if a person can only pass one test, how would you advise?
If we are talking about a sufficiently young age, about 25-35 years old, then, of course, it is worth passing the test "dietology" to find the best power system for a certain body. After 35 it is worth choosing "active longevity". And I would even recommend this test for women in 30, because there are such things as the exhaustion of ovaries, for example. This is an important factor in family planning, and the girl at such age is important to know their potential. Plus, such a disease, like Alzheimer, begins to form in 20-30 years before the first signs: Therefore, to prevent illness, you need to know your predisposition and take action - you can minimize the risks.
In addition to genetic tests, there are also allergic tests for the portability of products. And in that, in the other, certain products are selected, which are allowed, and which are not worth it. What are these two tests differ from each other?
The most important difference is the principle of testing. For DNA test, saliva needs, but the allergic panel is done in the blood. Plus, the genetic test looks at the most critical panels, and there are a lot of components in allergic. After all, he is prescribed when allergic has already been revealed and you need to find what it is. Therefore, for an allergic test, it is checked directly on the list, whether there are reactions to a certain food, pollen, animals, and so on.
That is, in the allergic test more panels are considered?
Usually begin with small, take the strongest allergens: cereal, chocolate, pollen plants, animal wool, lactose. If a strong allergy, then they are already watching more than indicators in order to find that it is specifically a reaction. Such tests are not cheap, because the number of panels can reach up to 50-70. You can do differently, take the "Exception," method, it works in many situations. The bottom line is that the suspect product is excluded from the diet for two weeks, and we observe how a person feels. Next, the product is again introduced and, again, we look at well-being. There is a negative reaction, then the product is cleaned again: if the symptoms really go, then it is desirable to exclude such a product from the diet in general.
This is an eliminational diet, yes?
Yes, it is she. I would recommend it at all, even if allergies are not observed. In any case, at the moment there are no DNA tests for all products. But for the same product, different people will respond absolutely differently. Take, for example, a pear, she has a high glycemic index. For one diabetics, this can raise the level of glucose by 20 units, and another is only 3-4. And with the help of such a diet, you can track how the body responds to a particular product.